Nano-aAPC disassociation rate after culture in a magnetic field did not decrease (Supplementary Figure 3D), suggesting aggregate formation was not associated with an increase in TCR/MHC contacts, but rather aggregation of TCR nanoclusters bound to aAPC.
Within both treatment groups, A1C, blood pressure, cholesterol, and LDL improved significantly at 3 and 6 months relative to baseline, whereas HDL decreased (supplementary Table A3).
We observed that the average SemiSVR performance decreased as the level of similarity of the test PDZ domain to the closest PDZ domain in the training set decreased (Supplementary Fig. S4).
Immunofluorescence staining for phospho-Smad1/5/8 after BMP2/7 stimulation showed that phosphorylated Smad1/5/8 was still able to translocate to the nucleus in the absence of TAK1, though the total levels of phosphorylated Smad1/5/8 were decreased (Supplementary Figure S3D).
Post-treatment completion the percentage of women reporting severe hot flushes, night sweats and cold sweats decreased (Supplementary appendix: Figures A2, A3, A6); however, patients continued to report poor sleep beyond treatment completion (Supplementary appendix: Figure A1).
In the presence of 2 µM ClpX, the amount of FtsZ in the pellet at all protein concentrations was decreased (supplementary Fig. S2, panel B).
In this case, the numbers of NF- κB immunostaining cells were decreased (Supplementary data, Table S2).
As predicted, co-precipitated KIF3A was decreased (Supplementary information, Figure S1C).
We confirmed that after blocking Prmt1 activity, methylation of endogenous Fus is decreased (Supplementary Material, Fig. S2B).
Something similar occurred in maize grain yield, except for SVC-lin, which increased as the percentile decreased (Supplementary Figure S1B).
