Exact(3)
Sonication is a powerful approach that can be used to decrease particle size, but one disadvantage of this technique is that strong mechanical treatment can also degrade the lipid-water structure and reduce drug loading capacity.
Prior to encapsulation, DNA may be condensed with cationic polymers to decrease particle size, protect DNA from degradation, promote interaction with cell membranes, and facilitate endosomal release via the proton sponge effect.
Inhaled treprostinil is administered via ultrasonic nebulizers to decrease particle size, thus allowing drug delivery to distal airways and fibrotic pulmonary arterioles.
Similar(57)
The decrease in toughness with increasing functionality was attributed to decreasing particle size.
Previous research has shown that increasing WCGF in the diet decreased ruminal pH, likely due in part to decreasing particle size as forage inclusion rate decreased.
Decreases in the blocking temperature can be caused by poor crystallinity (e.g. due to decreasing particle size) or by association with organic complexes.
Mastication aims to decrease particle-size distribution in the food bolus and forms a cohesive bolus with the saliva in order to facilitate swallowing.
In addition, further increasing the milling time to 60 min did not remarkably decrease particle size (Additional file 1).
The low saturation magnetization of the ferrite NPs is generally believed to be due to the decreased particle size and the presence of an anti-ferromagnetic layer on the surface.
BET experiments indicated that S-doping could inhibit particle-to-particle sintering, resulting in an increase in the surface area due to the decreased particle size.
The solid particle shrinks due to the dissolution and consequent reactions and the film becomes thinner and thinner due to the decreasing particle size.
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