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LoEs conjoin different (types of) studies that are used to critically test the hypothesis.
To critically test this theory absorption experiments of ammonia in water were conducted in a stirred cell.
The genetic architecture of several important traits is now known for threespine sticklebacks [3 10]; thus, ninespine sticklebacks provide a unique opportunity to critically test whether similar or different chromosome regions control similar phenotypes in these lineages.
Further studies are needed to critically test these possibilities.
To critically test the observed amplitude differences, we analyzed the amplitude under long and short days in more detail, by an off-line analysis of subpopulation activity.
To critically test if the furR3I allele does increase Mtz resistance, a chloramphenicol resistance gene (cat) was inserted downstream of a wild type (wt) fur gene by a direct PCR method [27], [28].
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To critically examine and test the strength of this system, we designed an RCT, together with an economic evaluation to investigate whether treatment according to this system is more cost-effective than usual care in reducing pain and improving functioning in patients with subacute and chronic LBP in primary care.
However, this hypothesis still needs to be critically tested.
A role for Gi has been proposed by various investigators but has yet to be critically tested beyond the application of pertussis toxin in co-treatment assays and this contrasts with a crucial role for Gq/11(White et al. 2008).
Several AD prevention trials that are currently under way or soon to be enrolling subjects will critically test the utility of these biomarkers in these pivotal studies and potentially the willingness of the FDA to use surrogate markers in lieu of cognition or functional changes as trial endpoints.
It is then possible to design appropriate in vitro experiments that critically test the most dominant mechanical characteristics existing in vivo.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com