Moreover, Rac1, which is activated by EphA4-ICD, has been reported to control the activity of the p21-activated kinase (PAK) pathway, leading to memory impairment (Zhao et al., 2006).
The SCN uses a continuously active glutamatergic projection and a rhythmically active GABAergic projection to control the activity of the sympathetic pre-autonomic neurons in the PVN.
Using genetic engineering, researchers are making the microbial rhodopsins more sensitive to light, improving their on/off rate and speeding up their recovery after activation, all of which are enabling them to control the activity of complex neuronal circuits with unprecedented and increasing precision.
Several factors are suggested to control the activity of WASP proteins by promoting its conversion from an inactive to an active form [10], [15] [16].
[A1.] RNA interference is not the only new way to control the activity of genes.
The sites of variation discovered by DeCode and the two other groups do not lie in genes and for the most part have no known biological function, though some are conjectured to control the activity of nearby genes.
DNA-mediated assembly was employed to control the activity of a multidomain enzyme.
The ability to control the activity of intracellular signaling processes in live cells would be an extraordinarily powerful tool.
The facial nucleus (FN) has been known as a motor nucleus to control the activity of the facial skeletal muscles by its efferent somatic motoneurons.
Bacteria have evolved complex regulatory networks to control the activity of transcription and translation, and thus the growth rate, over a range of environmental conditions.
Additionally, intracellular ROS can participate in signaling effects to control the activity of protein kinases and phosphates and regulate gene expression, and thus induce cell apoptosis and cell death [30,31].
