To formally test whether peptide-pulsing provided too brief a T cell stimulus to drive immature B cells to a stage at which they could differentiate in vivo, the experiment was repeated using HELcyt [ 15] in addition to peptide pulsing, with a view to ensuring continuous presentation of the MCC87 103 epitope by HEL-specific H-2bk B cells.
This rebound toward the previous winner after a temporary tendency toward the opposite percept is even more pronounced if one externally forces perception to the opposite interpretation by means of a disambiguated stimulus, instead of waiting for a spontaneous switch to occur during continuous presentation (Supporting Text S1, Figure S3).
The amino acid sequences of the peptides of neighboring spots were overlapping to ensure the continuous presentation of the complete cMyC sequence on the membrane.
Our second experiment was similar in design to the first one, but continuous presentation episodes were allowed to include up to four perceptual switches instead of just one.
Importantly, the predictions of this resource re-allocation model are not restricted to retention-intervals (i.e., gaps), but extend to distracters presented during the continuous presentation of a timed signal.
However, although attenuated, also the time bias associated with the animate context persisted over at least 5 consecutive static trials (corresponding to ∼22 s of continuous presentation of the still character).
It is well-known that chronic viral infections with continuous presentation of viral proteins to the immune system can lead to T-cell exhaustion.
To accomplish this on day 1, arm position information (i.e. cursor) was linearly faded from continuous presentation on trial 1, to only a 200 ms duration presentation every 2s by trial 19.
A change from superimposed orientations to a single orientation has 2 underlying constituents: A switch from one orientation to blank (off-component), and an overlaid continuous presentation of the orthogonal orientation (sustained, adaptive component).
Sessions consisted of blocks of intermittent presentation of an ambiguous stimulus, interleaved with periods of continuous presentation where perception was allowed to switch spontaneously.
