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One important perspective to comprehend the functions of PK2 in regulating the circadian system is to explore the characteristics of PK2-expressing neurons in the SCN and their connections in the context of neuronal circuitry.
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Specifically, network modeling was used to analyze and to comprehend the functioning of the distribution network better in terms of diagnosing problem areas, such as supply discontinuity, leakages and replacement of worn out pipes.
The ultimate goal of systems biology is to delineate and to comprehend the functioning of complex biological systems in such details that predictive models of human diseases could be developed [ 28].
Recent studies have addressed deregulation of microRNAs in the context of HNSCC, suggesting that these molecules could be used to improve diagnosis and the outcome of this disease [ 5]. Cell models are being broadly used in order to comprehend the function of specific miRNAs in this disease, but there is no current information on the miRNA content of these cells.
In order to comprehend the role of those transcripts played in the biochemical process, we assigned enzyme functions and enzyme commission numbers to reconstruct anabolic and catabolic pathways through linkage to biochemical pathways in the KEGG database [ 30].
To comprehend the role and mechanism of Tau pathology in AD, it is important to understand the normal function and processing of the Tau protein and the abnormal posttranslational processing of Tau in tauopathies.
To further comprehend the functions of these newly identified species-specific Vvi-miRNAs, it was essential to search for their target genes.
In this regard, our model of liver-specific deletion of Smad7 can serve as a useful tool to comprehend the biological function of endogenous Smad7 in the liver as well as in liver diseases.
We selected 186 terms as significantly enriched terms for D/ND and 155 such terms for DT/D to further comprehend the function of the differentially expressed genes with a cutoff FDR of 0.05.
To comprehend the distribution of functions in the CEG clusters, the distribution of COG codes in CEG was analyzed.
The objective of this paper is to use transfer functions to comprehend the formation of band gaps in locally resonant acoustic metamaterials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com