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One of these was determined to be progression of pre-existing concomitant squamous-cell carcinoma of the lungs and not metastatic MM.
The significance and relevance to BE progression of methylation of each gene may vary.
Obstructive pneumonia due to lung cancer was considered to be progression of lung cancer.
Note that the appearance of one or more new lesions is also considered to be progression.
The candidate biomarkers discovered in this cross-sectional cohort may turn out to be progression biomarkers, but they need to be confirmed in a longitudinal cohort.
Progression-free survival was censored at the date verifiable to be progression free, and OS was censored at the date of last follow-up.
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If ≥ 18 of 30 assessable patients are observed to be progression-free by 3 months, the study would have 80% power and 0.18 significance level.
At this point those who relapse enter a state of non-resectable metastatic GIST and are assumed to receive successful treatment with imatinib for approximately two years and, during this time, they are assumed to be progression-free.
Histopathologic assessment of dysplasia in BE is currently the most widely accepted parameter with which to predict BE progression.
Maybe it seems to be a progression, but there are no guarantees in life".
"That seems to be the progression — people move from Brooklyn to Staten Island, and then Staten Island to New Jersey," said Nicholas Polly, a local civic leader.
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