Nevertheless improvement of the design and material quality of the MQW microcavity will be necessary to observe the strong coupling.
A larger sample size may be necessary to observe an effect.
However, introduction of IRS-1 or -2 expression in T47D-YA cells was sufficient to introduce sensitivity to αIR-3, suggesting that expression of appropriate adaptor molecules, in addition to functional receptor, may be necessary to observe a response to therapeutic agents targeting IGF-IR.
As adaptor molecules are important components of IGF-IR signalling (Zhang and Yee, 2000; Sachdev and Yee, 2001), we propose that expression of the appropriate adaptor molecules, in addition to a functional receptor, may be necessary to observe a therapeutic response to agents targeting IGF-IR.
Better magnification would be necessary to observe the details.
Longer follow-up will be necessary to observe the effect of concurrent administration on cardiac toxicity.
However, silencing of multiple TGAL genes may be necessary to observe clear phenotypes.
Nonetheless, it would be necessary to observe feeding behaviours directly and quantify the levels of disturbance to confirm this hypothesis.
Multiple factors may be necessary to observe the evolution from acute T. whipplei primary infection to chronic infection.
An underlying diabetic phenotype might be necessary to observe any cardio-protective effects of ViL through its anti-inflammatory potency.
