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12 Human NEU3 has been found to be almost specific for gangliosides with hardly any action on glycoproteins, glycopeptides, or 4MU-NeuAc that are considered as good substrates for other sialidases in in vitro activity assays.
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Some studies indicate that the diagnosis of adenomyosis is rare in adolescence [10] and features of classic adenomyosis are not typical [11], with cystic adenomyosis being almost specific to adolescent and young women [12].
In addition to type II collagen, the second main component of the extracellular matrix of articular cartilage is aggrecan, which, like collagen type II, is almost specific to this tissue.
Using WhiB as a probe in one-way blastp searches of all the translated actinobacterial genomes, paralogues were sometimes very abundant: in an extreme case, Rhodococcus jostii possessed 30 wbl genes, all but five of them being almost specific to this organism or genus.
A study from the USA has reported that S. Saintpaul was almost specific for turkey meat rather than chicken, beef and pork samples [ 11].
One reason, which accounts for maintenance of Prx could be, that they can reduce a wide range of alkyl hydroperoxides [ 30], while APx isoforms are almost specific for H2O2 [ 4].
However, the t1-nucleotide binding pocket is large enough to accommodate any of the four natural RNA bases, and the contacts between Ago2 and t1A appear to be almost entirely non-specific.
But the details of nutritional requirements were either so general as to be almost irrelevant, or so specific that they were rarely transportable from one ecosystem to another.
The specific surface area of 25 nm particles was calculated to be almost three times larger than the specific surface area of 85 nm particles.
T415I and T418I variants were identified to be almost 11 and 27 times more specific for ABTS than for SGZ compared with the wild type.
It appears to be almost impossible to expect that a specific rub-in technique or "responsible application" can ensure that all or at least most hands are completely covered with the alcohol-based hand rub.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com