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Cyclin D is commonly found to be aberrant in cancer in terms of mutation, amplification, and/or overexpression.
RB1 has been reported to be aberrant in approximately 20% of breast cancer cases[4], [5], and to be associated with a poor disease outcome[5], [6].
The methylation of the PHD3 promoter in these carcinoma cell lines appears to be aberrant since insignificant DNA methylation was found in the non-transformed cell counterparts of prostate and mammary epithelial cell lines NPrEC and HME1 respectively.
Many of the mammalian mapping studies have been performed in embryonic stem cells, which are known to contain 5-hmC [14], or in cancer cell lines, in which DNA methylation is known to be aberrant [6] [9].
Finally, the integration of mutation data with aUPD data provides strong evidence that many more genes than previously thought to be aberrant in breast cancer and which await discovery and could include useful new therapeutic targets.
Compared to the adults, neonates are reported to be aberrant in their cellular immune responses, often biased to develop Th2 type immune responses and decreased ability to generate Th1 type immune responses [4], [5].
Similar(36)
Collapses can be aberrant or telling.
My experience may be aberrant.
The story of the murders, from beginning to end, was aberrant — in the amount of resources that the police invested in the case (compare it with the attention that the L.A.P.D. paid to the murders described in Jill Leovy's brilliant book "Ghettoside") and, especially, in the size and the skill of Simpson's defense-attorney "Dream Team".
Allison's research focussed on why T-cells failed either to recognize cancer as being aberrant or to attack it, as they do with microbes.
The presence of cysts with a respiratory-type epithelial lining in relation to abdominal organs is aberrant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com