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A medicinal chemist tinkers the drug design parameters to augment the potency, selectivity, and duration of the drug's action and to reduce the toxicity of the drug.
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In order to further augment the potency of the Combi-targeting approach, we recently designed RB24 (an acetoxymethyltriazene) to generate three inhibitors of EGFR and at the final stage of degradation a methyldiazonium species capable of damaging DNA (Banerjee et al, 2003).
The purpose of the present study was to examine the ability of CD19L sTRAIL, a potent and selective inducer of pro-apoptotic TRAIL signaling in CD19-positive BPL cells, to augment the anti-leukemic potency of low dose TBI in NS mouse xenograft models and CD22ΔE12xBCR double-transgenic (Tg) mouse models of radiation-resistant BPL.
They have the power to augment the script".
Then Pema brought lamb curry to augment the lamb innards.
Washington decided to augment the available technical intelligence.
Why does Bloom need to augment the self?
Notes were taken to augment the recording.
Reference lists from studies were used to augment the search.
The DNA damaging moiety augmented the potency in BRCA2 deficient cells by 2 20 fold.
As hoped, this compound augmented the potency of antibiotics in mice infected with this pathogen.Eventually, bacteria would evolve around such gimmicks, just as they evolved around antibiotics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com