Using this technology, we have been investigating mutations in several different gene segments to effectively attenuate potential vaccine strains allowing the safe production of vaccine to protect against the next pandemic.
Having such relevant instruments is very important to attenuate any potential bias arising from potential instrument non-validity.
Patients with psoriatic arthritis may be more likely to receive treatment with glucocorticoids; hence, to attenuate the potential impact of glucocorticoids on the risk of DM, we excluded patients with psoriatic arthritis in a sensitivity analysis.
We exclude workers aged 58 and more from our sample to attenuate a potential selection bias.
These findings are more severe in the nondependent areas of the lung, because of the "protective" effect of atelectasis and consolidation on the dependent areas of the lung in the exudative phase to attenuate the potential injury related to mechanical ventilation [7, 74, 84].
To attenuate this potential limitation, we chose a randomized crossover study design.
Intake of LCn-3PUFAs or magnesium above the median appeared to attenuate the potential effect of mercury exposure on diabetes risk (data not shown).
We argue, however, that our sample sizes, the magnitude of the differences, the diagnostic nature of our tests, and the time interval between pre and post-test (one semester) can contribute to attenuate this potential bias.
In a further series of experiments, we used the CXCR2 antagonist AZ10397767 at a concentration of 20 n M to attenuate any potential signalling effect resulting from the activity of additional, closely related CXC-chemokines to IL-8 (e.g., CXCL1).
While in resource-rich countries the above difference in mortality may almost entirely disappear as rescue therapies are applied to attenuate any potential adverse effect of fluid overload (ARDS, pulmonary edema, acute kidney injury), there is now concern that such therapy may not be as beneficial as previously believed.
