We were able to confirm apoptosis, but intriguingly this occurred prior to any appreciable effect on mitochondrial protein synthesis or on the steady-state level of most mt-mRNAs.
Mr. Perry had been for Newt Gingrich in the presidential race, to no appreciable effect.
President Assad himself has been under EU sanctions for almost a year, to little appreciable effect on his policies and the bloody crackdown he has implemented against Syrian revolutionaries and civilians.
There is little to no appreciable effect on flavor.
Due to its appreciable effect on phagocytosis and maturation of LB, we next investigated whether exogenous Hsp70 can also lead to increased uptake of mycobacteria and maturation of mycobacterial phagosomes.
Interestingly, longer-term exposure (48 h) of C6 glioma to ATP had no appreciable effect to alter mRNA expression for any of the P2YR (data not shown).
Multistage designs involving large numbers of sequence variants (∼300,000) and relatively large samples sizes (several hundred cases and control subjects) will be essential to reliably detect alleles with appreciable effect sizes (2-fold increase in relative risk).
In summary, the fixation of mutations is an evolutionary process that is driven by selection and drift and thus occurs on relatively long timescales compared with the generation time of individuals, so that eDNA turnover has to be commensurately slow to have any appreciable effect.
A defendant's decision whether to testify does not seem to have any appreciable effect on the outcome, as Mr. Whitman's conviction shows.
Smoothing parameters from 10 to 0.001 were tried and found to have no appreciable effect on the branch lengths on the tree.
Many analyses, though, suggest that, to have an appreciable effect on the oil sector, carbon taxes would have to be quite high — in the neighborhood of two dollars on a gallon of gasoline — precisely because today there are no readily available substitutes for gas or diesel or jet fuel.
