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The literature on biomarkers for treatment response is largely based on secondary analyses of studies designed to answer primary questions of efficacy, rather than on a planned systematic evaluation of biomarkers for treatment decision.
The "Just-in-time Information" (JIT) librarian consultation service was designed to provide rapid information to answer primary care clinical questions during patient hours.
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At least 300 participants will be included to answer the primary objective.
To answer our primary research questions, namely, "What are the factors at play around social debt during the software lifecycle?
Estimating the required sample size for a study is necessary during the design phase to ensure that it will have maximal efficiency to answer the primary question of interest.
This paper describes the process of model building for a section of the Dee valley in northeast Scotland, the development of software to support interactive exploration, and an experiment which was designed to answer some primary questions about validity and some secondary ones about local landscape preferences.
With this research, we sought to answer four primary questions: RQ 1: What are local health department director's perceptions of climate change and its potential public health effects?
Ensure the study design describes a method to answer the primary research question.
Binary logistic regression models were used to answer the primary and secondary study endpoints.
Physical activity levels will be measured at 12 weeks to answer the primary research question.
The sample size of 500 overweight and 1500 non-overweight children should be sufficient to answer the primary research questions.
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