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A third mechanism, FoSTeS, involves switching of the replicated strand to another replication fork, which could also happen at TGG repeats [ 14].
(2) After progressing for a short distance (78 bp), the nascent strand disengages and a microhomology-mediated migration to another replication fork occurs.
CDK phosphorylation of yeast Sld2 and Sld3, and their subsequent binding to another replication protein Dpb11, lead to replication initiation (Tanaka et al. 2007; Zegerman & Diffley 2007; Tanaka & Araki 2010).
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At this point, the molecules of signal are "ejected" from the replication origin and could be used to initiate another replication process.
The author of (Rong 2008) proposes another replication scheme for peer-to-peer video systems that adapts the number of replicas according to their utilization rate.
There are alternative explanations for the copying process, such as copying from one fork to another after DNA replication, or by involvement of the chitin induced DNA transformation between cells of the same clone forming a biofilm on chitin[14], [15].
Thus, it is not particularly informative to compare serum starved cells to G1 phase cells; it would have been more useful to add back serum and analyse the cells after they had committed to another round of replication.
Another mechanism to initiate replication consists in the specific nicking of one of the strands of a circular double-stranded DNA, producing a 3'-OH group available for elongation (KORNBERG 1980).
In this study, we examined the ability of gemcitabine to inhibit replication of another retrovirus, murine leukemia virus in cell culture.
This indicated that the amount of viral transcripts achieved in NHP/huPAR-2 cells did not correlate well with the infectious titer, and suggested that there may be another block to PERV replication in a late stage of the life cycle.
Once all papers are turned in, we will turn over your replication paper to another student, and assign you a replication paper to evaluate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com