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Woolly hair is characterized by the presence of fine and tightly curled hair and is also linked to another locus on chromosome 3q27.
For example, it is also possible that Idh-1 is linked to another locus which is under temperature-driven selection, and that the allele frequencies observed in nature reflect this linkage disequilibrium [ 5, 27].
This is consistent with classical Hill-Robertson effect theory, which states that a locus that is linked to another locus under selection will experience a reduction in effective population size [ 109].
Beside the possible occurrence of gene flow across the hybrid zone, data from levels of polymorphism, genetic differentiation and genealogical topology suggested that locus Chd1 may represent a candidate region associated with reproductive isolation, either directly or via linkage to another locus.
The IF data were further validated by Chip analyses of cells synchronized in G2. Figure 7E shows that Esco2 depletion resulted in marked reduction of PCH-bound Sororin but also in Sororin bound to another locus highly enriched for cohesin at the arm of chromosome 11.
For this confirmation, two groups were selected based on whether a homologous contig for a particular species is present in a region where a gene is not predicted, thereby checking if this gene is truly deleted from this locus or is still present, being either translocated to another locus or missed by the automated contig assembly.
Similar(54)
Phenotypic variation between individuals with the same disease alleles may be attributable to the genotype at another locus, which is referred to as a modifier gene.
This statistic measures whether two individuals being similar at one locus makes them more likely to be similar at another locus.
These results demonstrate that as little as a single base-pair mismatch is sufficient to direct the crisprTF to one locus while preventing activity at another locus.
For a clonal locus, this requires two rates of mutation: a slower one for the first mutation that sweeps to heterozygosity, and a faster one for the second mutation to occur before another locus takes its turn to adopt the first advantageous mutation.
The behavior of locus 1 was in some way similar to that of another locus (H2), sensitive to trans-inactivation by locus 271.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com