Moreover, the Euler/Lagrange approach was extended to allow time-dependent calculations of the flow evolving in a bubble column based on the Reynolds-averaged Navier Stokes equations together with the k ε turbulence model which was extended to account for turbulence modification by the bubbles.
The protocol allowed time dependent observations at 3-monthly follow-up visits.
Key concepts for success were to establish treatment conditions that are sufficiently mild to allow time for gene-dependent cell suicide to occur, and to deliver this stimulus uniformly and simultaneously to all cells in the sample.
Activation of these pathways will arrest normal cells in G1 via p53-dependent mechanism to allow time for DNA repair or they proceed to cell death if the damage cannot be repaired.
The proposed models are parsimonious, allow time-dependent hazard ratios, and facilitate comparisons between event-specific hazards and between covariate effects on different events.
Cumulative risk estimates of developing distant metastasis were obtained for specific subgroups of patients while taking into account the competing risk of dying from other causes and by allowing time-dependent effects (interaction with time since diagnosis) for age and tumour characteristics.
The increased crack growth rate during static far field loading is attributed to the stress relaxation of the inter-granular glass phase which allows time-dependent processes to occur ahead of the crack tip which lead to enhanced sub-critical crack growth rates.
The coefficient of variation (CV) of identified Ers across all patients was low (<0.005), as expected, as the 30-minute period allows time-dependent alveolar recruitment to fully occur and stabilise.
To examine the proportionality assumption, we used models that allowed time-dependent relative risks and found no suggestion that HRs varied with time.
This method allows time-dependent evaluation of all changes with respect to the pre-drug condition.
The slow process allows time-dependent investigations of structure formation.
