This might lead to an underestimation of the clearance rate, but as the assessment was blind to treatment allocation it is unlikely to lead to a difference between the two treatments groups.
Although the investigators and data analysts were blinded to treatment allocation, it was not possible to mask the interventions from the patients or the clinicians delivering care.
As rehabilitation studies are rarely masked to treatment allocation, it is problematic for parents to report perceived QOL without knowledge of treatment allocation, introducing bias.
The main limitation derives from the fact that although GPs will be blinded to patient allocation, it is presumed that they will easily be able to identify which group the patient has been assigned to in the follow-up assessments.
If epigenetic asymmetries of the early embryo are related to lineage allocation, it is still uncertain whether they are a cause or a consequence for lineage choice.
For some academics and the IBoD researchers, the ultimate value of the IBoD study lay in its capacity to inform resource allocation: " It's about establishing and confirming priorities"; " it was a good and useful kind of thing in sort of priority setting and this sort of stuff"; and " then people could decide where to target resources to make the biggest difference".
While this enabled each node to perform its own allocation, it lost out on the opportunity to redistribute workloads across the data centre infrastructure.
When brought to initial permits allocation, it provides the most probable (or fair) allocation among multiple countries.
But if the political conversation about disability is limited to debates about resource allocation, it leaves power in the hands of the able-bodied majority.
Above all, perhaps, in shifting the democratic to market-based principles of allocation, it favours those who are strongest in their control of the market, and who also happen to represent the social basis of Conservatism.
