Twenty-nine TF are potentially able to affect the expression of the other 126 DEG more highly expressed in PAR vs. MFP, based on the IPA knowledge base.
Nevertheless, this viral protein is able to affect the expression of several cellular genes that are implicated in immune response.
The n-cadherin peptide was found to affect the expression of pluripotency marker, alkaline phosphatase, in murine embryonic stem cells cultured on n-cadherin peptide containing hydrogels in a concentration dependent manner.
However, the architectural features of the scaffolds were found to affect the expression of bone specific genes, suggesting that specific scaffold groups could be more suitable to direct human iPSC-MPs in vitro toward an osteoblastic phenotype.
The full effects of deletions and inversions on local gene expression may well be highly complex, as the altered topology at SCRaMbLEd loci is also likely to affect the expression of neighbouring genes through multiple mechanisms, such as changes in local nucleosome positioning, disruption of nearby promoter regulation and repositioning of genes relative to one another.
Low serum vitamin D, which influences MS course and disability, seems to affect the expression of histone-modifying enzymes [15].
We show that wingless acts through dishevelled and armadillo to affect the expression of the homeobox gene engrailed and cuticle differentiation.
For example, Li is known to affect the expression of two key circadian genes, inhibiting GSK3β expression and activating Clock transcription.
These results indicate that the overexpression of OsMADS45 activates the expression of RFT1 at early development stages, but fails to affect the expression of the upstream genes.
Notably, age has been found to affect the expression of CI in several systems, sometimes in relation with Wolbachia density in testes [17], [18], [19], [20], [21], [22].
IL-23 expands the pool of TH17 cells [27], but Baicalin failed to affect the expression of IL-23 receptor during TH17 differentiation (Figure S2A).
