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Although TpA codons were always more used than expected in Ile, Val and Leu boxes (with the exception of TTA Leu codon), G-ending codons were always preferred to A-ending ones in Leu TTR and Val CTN codons, probably due to a compensatory TpG increase caused by the extreme CpG under-representation found in this virus group [60].
Second, the trend, where both increase and decrease are obvious as GC content varies, is mostly definable based on the GC content of the codon endings, e.g., G-ending and C-ending codons increase as genomic GC content goes up and the opposite trend belongs to A-ending or U-ending codons.
They come to an end".
Maintenance came to an end.
Summer came to an end.
She was a means to an end.
They are a means to an end.
This was a means to an end.
And if it comes to an end?
His term is coming to an end.
"Has drug trafficking come to an end?
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