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During the titration period, seven patients receiving glipizide versus none receiving dapagliflozin were down-titrated to receive no study treatment.
Patients beginning treatment with either repaglinide or metformin entered an 8-week titration period (to optimise dosage: repaglinide, 2 4 mg/day; metformin, 1500 2500 mg/day) followed by a 12-month treatment period.
Chemical denervation with botulinum toxin A is the current standard of treatment for spasmodic dysphonia, but dosage is determined individually after a titration period that can take months to years.
The patients took the CBD for 12 weeks, after going through a two-week titration period.
Following implantation, a "titration" period allows for refinement of stimulation settings.
The approved regime of VRC is 1 mg for 12 weeks, starting with a 1-week titration period [6].
Patients then undergo a therapy titration period during which stimulation parameters are to be adjusted bi-weekly.
Topiramate-associated AEs are mild or moderate in severity and occur at consistently higher rates during the titration period compared to the maintenance period of the double-blind phase.
Three settings were delivered in a randomized fashion (1 1 1): full stimulation (i.e. customized stimulation parameters established during the therapy titration period), sub-perception stimulation, and sham stimulation.
Berhanu 2007 used a four week titration period for insulin (Humalog, Humulin 70/30 or Humulin N) and defined a target fasting plasma glucose of less than 140 mg/dL while avoiding hypoglycaemia.
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The treatment was initiated with a 7-day cross-titration period.
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