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Titrating these ECMO settings can involve multiple steps because, frequently, the initially chosen parameters will not produce the desired result in terms of blood gases, leading to at least one more cycle of parameter change and blood gas analysis.
It is not unreasonable to assume that an increase in transposon transcripts, similar to what has been shown for competing endogenous RNA (ceRNA) (Salmena et al. 2011), may reduce the availability of microRNAs by a sponge effect, titrating these small RNAs and then changing the regulatory networks in which they are involved.
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In addition, we assessed the factors used to titrate these settings including respiratory rate or partial pressure of carbon dioxide (PCO2) for THigh and TLow and oxygenation or plateau pressure for PHigh.
We then titrated these peptides against a 15N-labeled CypA sample, and derived from the chemical shift differences a dissociation constant (Figure 7A D).
We titrated these small molecules into separate samples of the [C]-methylated Btk KD and acquired [H,C] HSQC spectra at increasing concentrations of inhibitor.
Physicians should realize that symptom relieve is of utmost importance in these patients by titrating the dose of diuretics as optimally as possible.
Two calibration curves are prepared based on titrating the reaction mixtures of both these sets of experiments with NaOH, and it is found that there is negligible change in both the calibration curves.
These results suggest that β-catenin contributes to pluripotency not only by titrating the activity of Tcf3 but also by promoting the efficient membrane association of Oct4.
Because most trials were short, less than four weeks, and because few titrated the dose, these results have limited applicability to longer-term use of opioids in clinical practice.
The "binary titration" experiments, using H,N HSQC, were performed with MDM2, titrated against these two enantiomers.
Treg were titrated into these cultures.
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