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Identification of specific genes whose DNA methylation pattern is associated with tumor phenotypes, including stage and grade also illuminates the particularly important biological processes and pathways required for genesis of these histologically defined tissue states.
Multiple hormones interact to alter tissue states and to activate genes involved in these processes.
After terminal differentiation, mesenchymal or epithelial tissue states are generally stable.
Imaging these properties over a wide area will give clinicians a tool for assessing the boundaries between different tissue states.
The recently developed theory of the expandability of adipose tissue states that this expansion is not unlimited.
The resulting intensity spectra are measured and serve for developing classification algorithms to automatically characterize the tissue states [ 8– 10].
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Quantitative spectral analysis of the radiofrequency (RF) signals that underlie grayscale EUS images can be used to provide additional, objective information about tissue state.
It is thus of utmost importance to incorporate this deformed and loaded tissue state into the computational models, which implies solving an inverse problem (calculating an undeformed geometry given the load and the deformed geometry).
This stratagem may provide a novel pathway for developing multi-functional coatings for controlling the local delivery of therapeutics at sites where the presence of various enzymes exist as a function of tissue state.
Yang et al. are among the researchers who challenge the notion that the glans is not formed of erectile tissue, stating that their dissections clearly show glanular vascular spaces, although not as prominent as those in the clitoral body.
Note that the CEL file effect, c, is nested inside tissue state.
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