Your English writing platform
Discover LudwigSimilar(60)
The majority of CellSearch® images analyzed were from patients with M0 breast cancer, with <5 CTCs in their blood sample and from patients for whom blood sampling for CTC detection was performed before the administration of systemic treatment (Table 1).
In a study comparing two commercially available assays (CellSearch® and AdnaTest®) in the same metastatic BC patient samples, the concordance between the two assays was 64% for CTC detection and 50% for HER2- positive CTC detection [ 42].
This model allowed taking into account the major challenges for CTC detection and enumeration: (1) the discrete process; (2) the Poisson-distributed sampling error; (3) the overdispersion; and (4) the high number of CTC counts equal to 0. This report represents the first use of a cell lifespan model to describe CTC kinetics.
blood samples per patient, method of CTC isolation and enrichment, molecular technique, target gene, and/or antigen used for CTC detection, in vitro sensitivity of each molecular method (if assessed), and no.
Despite the numerous methods for CTC detection a major question that arises is whether these assays give the same information when analyzing the same clinical samples.
The correlation remained significant when the cut-offs for CTC detection with the CellSearch were set at ⩾1 and ⩾2 CTCs (Table 2).
Stott and colleagues [ 34] recently reported improved sensitivity of the CTC-chip for CTC detection in patients with localized prostate cancer.
Send a tissue sample for biopsy.
From each patient we obtained peripheral blood for CTCs detection and corresponding paraffin-embedded tumor tissue.
There are two main methods for CTCs detection which are PCR-based assays both exploiting tissue and/or tumor specific antigens and immunological assays using monoclonal antibodies [ 48].
From each patient we obtained peripheral blood for CTCs detection on the day of surgery and corresponding paraffin-embedded tumor tissue.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com