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Chitin and chitosan are biopolymers from renewable resources, obtainable from shells of shellfish, the wastes of the seafood industry.
Importantly, like cell lines, PDXs provide a renewable tissue resource.
Control tissue (CON1 CON8, Table 1) was provided by the UK multiple sclerosis tissue resource, London.
Thus, these markers may be useful for predicting gemcitabine chemosensitivity for unresectable patients with tissue specimens obtainable only through a biopsy.
Making a comparison of the CGH profiles between the established cell lines and their parental tumor tissue specimens is practically impossible, because the source tissue specimens are no longer obtainable.
‡GTeX (Genotype Tissue Expression Resource) results were queried for 9 tissues on August 6, 2013.
Large numbers of hMSCs can thus be acquired from small samples of easily obtainable tissues like fat and bone marrow.
(Storing and safeguarding that tissue requires resources, and Planned Parenthood charges researchers for the costs).
When the appropriate resources are obtainable, the ML approaches perform better than dictionary and rule-based approaches.
From a clinical perspective, finding specific disease markers or biomarkers in such fluids represents an attractive alternative to tissue samples, due to the relative ease and less invasive nature of collection, and the large volumes that are normally obtainable.
Surely, a blanket was obtainable.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com