Sentence examples for tissue outbreak from inspiring English sources

None of these mutations were found in the soft tissue outbreak strains CRM-0020 and GO 06 from Brazil or the M18 strain.

Alignment of the MmpL family protein with distinct MmpL proteins described above for the Seattle cystic fibrosis outbreak and the Brazil soft tissue outbreak showed diversity at several amino acid residues in all 3 proteins.

Eighty-six SNPs were present only in strain CRM-0020 (softissueue outbreak) from Brazil, including nonsynonymous mutations in an MmpL family protein; transcriptional regulators; and lipid, amino acid, and energy metabolism genes.

We identified unique single-nucleotide polymorphisms in cystic fibrosis and soft tissue outbreak strains, separate single-nucleotide polymorphisms only in cystic fibrosis outbreak strains, and unique genomic traits for each subset of isolates.

Having shown high-level relatedness among Papworth and Seattle cystic fibrosis outbreak strains and their relatedness to the soft tissue outbreak strains from Brazil, we also searched for genomic regions ≥200 nt outside the core genome that were specific to subsets of isolates.

Addition of the soft tissue outbreak strain CRM-0020 from Brazil (n = 11) (32 ) decreased the core to 4,231,390 nt, and adding the related outbreak strain GO 06 from Brazil (n = 12) (8, 33 ), led to an additional decrease in the core genome to 4,043,718 nt.

Although the SNPs described for rpoB and secA1 were not 100% specific markers for the outbreak strains, these SNPs could be used for first-level identification of newly isolated strains as possibly being related to cystic fibrosis clusters or soft tissue outbreak strains from Brazil to be confirmed by a second assay.

Multiple alignment of secA1 sequences among available M. abscessus subsp. massiliense genomes showed a G→T substitution at position 820 (by using the secA1 gene MAB_3580c from the M. abscessus subsp. abscessus type strain) shared by the Papworth and Seattle cystic fibrosis outbreak strains but not by the soft tissue outbreak strains from Brazil or additional unrelated strains.