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At this stage, it was not clear whether these tissue memory cells were resident in the tissue or were part of the circulating pool of memory T cells and were just passing through the tissue.
Here, we use a unique human tissue resource to determine whether human tissue memory T cells constitute a distinct subset in diverse mucosal and lymphoid tissues.
This may be due to what some authors call 'soft tissue memory'.
Or maybe it could even act as a sort of "tissue memory" in conjunction with nerves.
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Gebhardt, T., Palendira, U., Tscharke, D. C. & Bedoui, S. Tissue-resident memory T cells in tissue homeostasis, persistent infection, and cancer surveillance.
Biting into a really crisp apple, one feels, in the words of Edward Bunyard, the author of "The Anatomy of Dessert," "a certain joy in crashing through living tissue, a memory of Neanderthal days".
Webb, J. R., Milne, K., Watson, P., Deleeuw, R. J. & Nelson, B. H. Tumor-infiltrating lymphocytes expressing the tissue resident memory marker CD103 are associated with increased survival in high-grade serous ovarian cancer.
We aim to elucidate the underlying role of tissue resident memory T cells (TRM) in immunopathogenesis of PSC and the mechanistic basis for the coexistence of IBD with PSC.
The generation of tissue resident memory (TRM) cells at the body surfaces to provide a front line defence against invading pathogens represents an important goal in vaccine development for a wide variety of pathogens.
Recent studies have shown that tissue resident memory T cells (TRM) are critical to antiviral host defense in peripheral tissues.
Double negative CD21−CD27− B cells isolated from human peripheral blood have also been reported recently as tissue like memory B cells, with low in vitro proliferative responses compared to other B cells [38].
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