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Our 3D system provides a structure that exploits embryonic processes such as tissue induction and condensation.
In addition, we discuss the importance of studying endogenous models of tissue induction and present some of the current in vitro and in vivo approaches to growing complex tissues/organs for craniofacial reconstruction.
By combining strategies from ectopic tissue induction models with methods from tissue engineering, new approaches for studying lymphoid tissue development and immunotherapy may be possible.
The induction of bone develops a mosaic structure in which members of the TGF-β superfamily singly, synergistically and synchronously initiate and maintain tissue induction and morphogenesis.
The induction of periodontal tissue regeneration develops as a mosaic structure in which the osteogenic proteins of the TGF-β superfamily singly, synergistically and synchronously initiate and maintain tissue induction and morphogenesis as a recapitulation of embryonic development.
Amino-acid sequence variations amongst BMPs/OPs in the carboxy terminal domain confer the structure/activity profile responsible for the pleiotropic activity that controls tissue induction and morphogenesis of a variety of tissues and organs by different BMPs/OPs which are helping to engineer skeletal tissue regeneration in molecular terms.
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The development of a nephron involves a series of reciprocal tissue inductions between the ureteric bud and the metanephric mesenchyme.
Hence, in those instances in which bacterial motility may be required for efficient colonization of tissues, induction of the injectisomes should be triggered at a later stage.
These data suggest that ALOX5 and 5-HEPE seem to contribute to adipose tissue Treg induction in vivo.
Pathways a, c and d are involved in infection-induced inflamed tissue involving induction of inducible form of nitric oxide synthase (iNOS), and subsequently generation of nitric oxide (NO) and superoxide (O 2 ·− ) and then peroxynitrite (ONOO−), which nitrated guanine (→ 8-nitroguanine), and 8-nitroguanosine (NitroGuo), as substrates of NOS or cytochrome c reductase, thereby generation of O 2 ·−.
The tissue specific induction of Foxp3+ cells in lung tissues prior to tumor development suggests that NNK-induced Foxp3+ T cells provide a permissive environment for the development of K-Ras-driven lung tumors.
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CEO of Professional Science Editing for Scientists @ prosciediting.com