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It turned out that the second patient had received tissue from the same donor.
The second processor that received tissue from the same donor found strep on 13 samples and impounded the samples.
Data have been technically validated on a contralateral dermal tissue from the same subject and compared with those from control healthy skin.
The latter are the haystack.A tissue of lies Comparison of healthy and cancerous tissue from the same individual will show which genes have mutated.
We identified the same somatic mutation in all three affected tissue samples that was absent in unaffected tissue from the same patients.
In the case of prostate tumors, the increase was 2-10-fold, compared with benign hyperplastic prostate tissue from the same patients.
Comparing the sequences with those from blood samples and healthy tissue from the same patients, they found 39 mutations specific for the tumor cells.
Next, the team looked for active genes in endothelial cells from colon cancers and from normal colon tissue from the same patients.
For RNA analyses, tissue from the same part of the liver lobe was used.
The confirmatory PCR studies were performed on tissue from the same animals used for the gene expression array studies.
The goal of the study was to compare the gene expression patterns between perihematomal and contralateral healthy tissue from the same individuals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com