Sentence examples for tissue exposure from inspiring English sources

For new and lasting tissue vascularization, prolonged tissue exposure to these factors could be critical.

Results of clinical trials in prostate cancer for instance demonstrate that the ability to increase the dose to tumor while reducing normal tissue exposure results in better cancer control and fewer side effects.

To establish a quantitative model for predicting OTC plasma and tissue exposure, a permeability-limited multiroute physiologically based pharmacokinetic model was developed in dogs.

Further investigation is needed to clarify whether this apparent lack of response results from limited tissue exposure or metabolic differences between species.

The highest tissue exposure was detected in lung tissue and it may primarily contribute to the pulmonary congestion in dead rats.

Moreover, peptide ligand-modified nanomedicines can potentially accumulate in the target tissue at higher concentrations than would small conjugates, thus increasing overall target tissue exposure to the therapeutic agent, enhance therapeutic efficacy and reduce side effects.

While high system drug levels are generally undesirable in lung targeted therapies, high blood levels in this rodent study could be indicative of increased pulmonary tissue exposure using BMP formulations.

The high-throughput experimental approach has also allowed for a specific training set of 263 molecules for a quantitative structure affinity relationships (QSAR) method to be developed, which has also been shown to be a predictor of ocular tissue exposure.

The risk of breast cancer, too, is about 16 percent lower among physically active women, perhaps because exercise reduces tissue exposure to insulin-like growth factor, a known cancer promoter.

Figure 3 Radioactivity versus time curves and tissue exposure.

Statistical t-tests were performed to evaluate differences in tissue exposure.