These mechanisms engender a tissue environment that favors normal stem cells over precancerous ones.
In addition, a number of activatable agents have been described that have different relaxivities based on the local tissue environment in vivo 13, 14.
Schmid, J. et al. Host tissue environment directs activities of an Epichloë endophyte, while it induces systemic hormone and defense responses in its native perennial ryegrass host.
The resulting destruction of the normal tissue environment promotes tumour growth.
Adipose tissue is a special tissue environment due to its high lipid content.
Cell encapsulating poly ethylene glycol) hydrogels represent a promising approach for constructing 3D cultures designed to more closely approximate in vivo tissue environment.
Herein, we developed a biomimetic fibrous hydrogel with tunable structure, stiffness, and composition to resemble the native vascular tissue environment.
Cellular responses relating to immunology, physical incorporation and the remodelling effect within the surrounding tissue environment are also discussed.
A major disadvantage of current synthetic implants is their failure to adapt to the local tissue environment.
There are many indicators of inflammation in Alzheimer's disease1: levels of immune molecules are elevated; neuron-supporting cells called glia react strongly to the abnormal tissue environment; and changes arise in the specialized vasculature of the blood brain barrier.
Due to reduced blood and tissue absorption, as well as reduced scattering in the turbid tissue environment, red light can readily penetrate at high intensity 2 3 millimeters from the surface of tissue43 enabling photocytotoxicity throughout large tumor masses.
