Sentence examples for tissue decline from inspiring English sources

Without it the tissue could not withstand the rigours of joint loading and its decreased abundance marks the onset of the tissue decline associated with the OA joint.

Moreover, some processes which are important for organismal fitness in youth may actually contribute to tissue decline and increased cancer in old age, a concept known as antagonistic pleiotropy (Campisi 2005).

But somatic cells in adult tissues do not maintain telomeres continuously, and these structures are reduced in length with age, until a critically short length stimulates cell death or senescence (which may contribute to tissue decline with aging).

Many studies focus on functional aspects of aging-related tissue decline, while structural details remain understudied.

These results suggest that telomere dysfunction may play a role in age-related lung tissue decline.

We speculate that this series of genes protect against age-related kidney tissue decline in the bowhead whale.

Over time the lung's ability to maintain and repair healthy tissue declines.

The hypoxic myocardium then cannot maintain cardiac scope and internal oxygen delivery to tissue declines.

Articular chondrocytes proliferate in monolayer culture, but the expression of the transcription factor SOX9 falls and the ability of the cells to reform cartilage tissue declines.

From the third decade onwards, cellular function in tissue declines and tendons are subjected to degenerative changes, making the aged tendon weaker and thus more susceptible to overuse (Kannus et al. 2005).

In the model, as Aβ concentration in the tissue declines, the balance between Aβ release/synthesis and Aβ uptake/catabolism tips towards net release/synthesis.