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Acute pain is as a warning signal that alerts us to noxious mechanical, chemical and thermal stimuli, which are potentially tissue damaging.
To elucidate the localization of tissue damaging protease activity, highly sensitive FRET reporters were employed that can discriminate between free (NEmo-1) and membrane-bound (NEmo-2) NE activity in CF-like lung disease (Fig. 1) [16, 23].
But unlike cosmic radiation or radon gas, plutonium can lodge itself inside the body and deliver tissue damaging alpha particles over a lifetime.
Tregs are believed to be crucial in adjusting response thresholds to microbial antigen as well as modulating tissue damaging immune reactions [20].
P. acnes produces a host of tissue damaging enzymes that may be able to destroy corneocyte membranes [ 26].
After six days in captivity most of cicadas were dead, although the tissue damaging due to feeding by the larvae was low.
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In the present study, the difference in the vvp gene encoding a tissue-damaging metalloprotease was investigated.
How the IMM fusion and cristae biogenesis protein OPA1 preserve mitochondrial function from a plethora of tissue-damaging insults and from respiratory chain inhibition is unclear.
Excessive activation of VEGFR-2 has been found to mediate tissue-damaging vascular changes as well as the induction of blood vessel expansion to support the growth of solid tumors.
Using a prospective study design, we examined the relationship between a tissue-damaging procedure (TDP; tape removal during discontinuation of an indwelling central arterial or venous catheter) and oxidative stress in 80 preterm neonates.
Alpha1-antitrypsin deficiency (AATD) is an underdiagnosed genetic disorder that results in early-onset emphysema due to low serum levels of alpha1-proteinase inhibitor (alpha1-PI), leading to increased activity of tissue-damaging neutrophil elastase.
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