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This material show promise for wound healing applications where regeneration of nervous tissue connections is desired, as it will act to prevent infection, allow oxygen to the wound site through micron sized pores, provide a nanotextured substrate material for nervous and tissue growth, and stimulate reconnection of nerve cells by electrical pulsing.
And yet, surgical dissection in vivo demonstrates that there are only tissue connections, simply a histological continuum without any clear separation between skin and hypodermis, the vessels, the aponeurosis and the muscles.
True integration can be achieved by designing smart templates made of biomaterials that not only act as scaffolds for cells to adhere and form new tissue, but also provide cues and signals to promote functional tissue connections.
By studying the TPC in isolation, without the essential soft tissue connections, Nummela et al. did not have the advantage of seeing the anatomic context of the TPC.
Meshes were investigated microscopically with regard to interstructural tissue connections and quantity of mesh adherent cells.
Severing the soft tissue connections from inside the braincase helped to loosen the tympanoperiotic complex as well.
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The reproductive behaviour of fishes is remarkably diversified: they may be oviparous (lay eggs), ovoviparous (retain the eggs in the body until they hatch), or viviparous (have a direct tissue connection with the developing embryos and give birth to live young).
This correlated to faster basement membrane (BM) formation and ultrastructurally defined dermo-epidermal junction including abundant anchoring fibrils for strong tissue connection.
Endoscopic high-frequency ultrasound of the larynx has been described: the larynx is depicted from the luminal side by filling the larynx and the trachea above the cuff of the endotracheal tube with 0.9 % saline to obtain sufficient tissue connection and prevent the retention of air bubbles in the anterior commissure [251].
This ROD model can be considered a new important tool for determining the complex multi-organ and multi-tissue connections between elevated GC levels and the development of metabolic syndrome and T2DM.
To investigate the inter-tissue connections at the gene expression level, we constructed a multiple-tissue gene co-expression network that contained 5148 nodes (QTT) associated with NEFA from the five tissues.
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