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The Scheuer system was applied in 100 patients – the surrounding liver tissue was not adequate to score in five patients – for grading and staging of peritumoral liver tissue (Brunt, 2000).
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In particular, the brunt of tissue damage in Alzheimer's disease and several diseases in the frontotemporal lobar degeneration (FTLD) spectrum initially falls on the temporal lobes, which are likely to contain mechanisms integral for voice analysis and recognition (Belin et al., 2004).
A pathologist blinded to the animal grouping evaluated the slides and scored each liver tissue specimen based on the criteria proposed by Knodell, Lee and Brunt [ 25, 37, 38] for steatosis, inflammation and fibrosis.
However, it is the resident macrophages and infiltrating macrophage-like cells that assume a pro-inflammatory phenotype, contributing to the brunt of pro-inflammatory cytokine production (e.g., TNFα, IL-6 and IL-1β) within adipose tissue [ 16, 17].
The tissues in the anterior segment of the eye, particularly the cornea, lens, and trabecular meshwork, bear the brunt of this oxidative stress due in part to their positioning in the eye and the avascular nature of these tissues.
The pathologic transformations of the adipose tissue in obese subjects, particularly increased cytokine and free fatty acid release, contribute to nonalcoholic fatty liver disease physiopathology (Brunt 2010; Tiniakos et al. 2010).
Brunt D, Greenberg B, Wankadia S, Trimble MA, Shechtman O.
Van Brunt Gallery, 137 Main Street.
Spending should bear the brunt.
Miners in London felt the brunt.
The customer service department bore the brunt.
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