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The recent design of ultra-broadband, multifrequency ultrasound transducers has enabled high-sensitivity, high-resolution contrast imaging, with very efficient suppression of tissue background using a technique called acoustic angiography.
In particular, FLIM allows to better differentiate between low level specific signals and autofluorescent tissue background.
Because of unreliable detection of negative nuclei against tissue background, detected positive nuclei were then related to the area of viable tumor tissue.
Regions of interest (ROI) were drawn on anterior and posterior gamma camera images to encompass the whole liver, up to two index lesions, and normal tissue background.
In contrast to these findings, there are two studies reporting no effects on the soft tissue background activity with chronically increased B-glucose in tumour patients [18, 19].
b Reference Raman spectra of pure SEPs (red: S420, gray: S421 and blue: S440) and tissue background with no SEP (black).
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The size or weight of a cell varies from different tissue backgrounds.
In an application to >100 cell lines, we deconvoluted the target signal patterns across the heterogeneous cancer cell collection, hence revealing pan-cancer correlations in their addiction signatures between both shared and unique genetic and tissue backgrounds.
The VOI was restricted to the region above soft-tissue background and applied separately to the images from each time point.
The use of the shunt removed problems of tissue-background activity, and the use of a light-tight probe with minimal gamma sensitivity refined the system.
Using Monte Carlo simulation of 99Tcm single-photon-emission computed tomography (SPECT), we investigate the effects of tissue-background activity, tumour location, patient size, uncertainty of energy windows, and definition of tumour region on the accuracy of quantification.
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