Sentence examples for tissue accessibility from inspiring English sources

Because of tissue accessibility, synapse elimination has been best studied in early postnatal life at the neuromuscular junction54 but is also known to occur in autonomic ganglia,55, 56 the cerebellum,57, 58 the retinogeniculate system59 and the somatosensory system60 by a common mechanism of axon pruning throughout the peripheral nervous system and CNS.

However, certain limitations apply to most of these systems, including leakiness of transgene expression, inefficient transgene silencing or activation, as well as limited tissue accessibility of transgene-inducers or their unfavourable pharmacokinetics.

The systems described here improve tissue accessibility and are sufficient for clinical skin imaging.

Considering the multipotency and tissue accessibility, ADS cells become one of the most attractive parental cells for reprogramming.

However, challenges exist with cancer biomarkers, including unsatisfactory specificity and sensitivity, difficult tissue accessibility, and ineffective test for detection.

Since our study was not based on a pre-selected patient cohort (with the exception of tumour tissue accessibility), this may account for the lower percentage of EGFR-mutated patients.

Circulating insulin-like growth factors (IGFs) are bound in complexes which affect their tissue-accessibility.

However, miR may represent promising markers, their application in the clinics is challenged by tissue biopsies accessibility.

Furthermore, it realises a streamlined cost effective network, ensuring tissue visibility and accessibility thereby improving the availability of large amounts of samples of highly specific or rare tumour types as well as providing contact opportunities for collaboration between scientists with cutting edge technology and tissue collectors.

Skeletal muscle is the most abundant human tissue and its accessibility makes it a good candidate for protocols based upon the delivery of stem cells as a medicinal product.

The ultimate toxicological manifestations of proteome inhibition are influenced by physicochemical characteristics that determine toxicokinetic outcomes (e.g., electrophilicity, metabolism, and tissue distribution) and accessibility to individual protein targets (e.g., steric hindrance).