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As in the other sortases, these residues are located at the ends of three neighbouring β-strands from the C-terminal β-sheet of Spy0129; Cys221 is at the tip of strand β7, His126 at the tip of strand β4 and Arg229 at the beginning of the antiparallel strand β8 (Figure 4).
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If you have thick, curly hair, odds are that without a deep-hydrating conditioner to make up for the lack of oils making their way from the scalp to the tip of the strand, you'll have dry, dull hair with a tendency to frizz.
Three of the four cysteines come from one loop in the structure of the protein, with the other one being at the tip of a β-strand in a different loop (3 + 1 arrangement).
A polar residue in the sensor 1 motif at the tip of the β4-strand (corresponding to N263 in budding yeast Cdc6) is also required for ATP hydrolysis in various AAA+ proteins (Wendler et al., 2012).
The "Diamonds" singer has dyed her bleach blond locks back to black and accented the tips of her strands with an icy shade of gray.
The tips of your strands are the most brittle and damaged (as they receive the least amount of natural oils), and are the most prone to breakage.
More distally, a leaf trace diverges from the tip of another rib with protoxylem strand (Additional file 2: Figure S2k, arrow) and is then surrounded by the secondary xylem (Additional file 2: Figure S2d, lower arrow, j).
Arrowheads indicate the tip of loop7 and arrows indicate strand-β3 (which connects to the P-loop), or the structurally equivalent region in the Myosin motor domain (indicated with *).
nytimes.com/physed GRAPHICS: 1.Telomeres: Longer telomeres -- the protective tips of a DNA strand -- indicate youthful, healthy cells.; 2.RUNNING: The telomeres of physically active older subjects are longer than those of their sedentary peers.
Since the expansion of the best picture category, there's been a near-annual slot for the previous year's big Sundance winner – a tip of the hat to the scrappier strand of "true" independent cinema that has yet to enjoy its big Oscar moment, as opposed to the polished mid-range indies that are now the Academy's bread and butter.
Arrow showing a protoxylem strand near rib tip of stem primary xylem.
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