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Careful selection of subgroups and adequate timing remain of the essence in this process.
Whether Icaritin (ICT), an active molecular compound from EFs, can exert beneficial effect on osteoporotic bone and whether the beneficial effect is also dependent on the intervention timing remain unknown.
Prenatal alcohol exposure (PAE) has been linked to poor pregnancy outcomes, yet there is no recognized standard for PAE assessment, and the specific effects of quantity, frequency, and timing remain largely unknown.
Fluctuations in Late Cretaceous climate were already influencing biotic change prior to the environmental upheaval at the Cretaceous Paleogene (K Pg) boundary, but their general nature, magnitude and timing remain controversial.
The details, however, of the mechanisms linking chromatin state and replication timing remain largely unknown [ 19].
Certain life stages are important for adipocyte hyperplasia and hypertrophy but the mechanisms controlling WAT expansion, and their timing, remain to be fully elucidated [ 24]. White adipocyte cell number is thought to stabilise towards the end of adolescence in non-obese humans and rodents [ 24], which suggests that conditions during this programming period could influence future adiposity.
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Just after his segment on "desert island condiments" – our Alan remains a pedant on Branston – his timing remained perfect on "dream dinner-party guests".
By Friday afternoon, timing remained uncertain.
Mr. Bush encouraged the idea today that the timing remained very uncertain.
Other details, including on timing, remained sketchy, but the news was fresh evidence of Beijing's determination to rein in property prices.
Even though Cameron's demand for the inclusion of the Greens has now been accepted, the Conservatives refused to confirm on Friday that they would participate, with one Tory source saying that the proposed timing remained a key objection.
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