Sentence examples for timing regulation from inspiring English sources

These results confirm a role for BAF250a in replication timing regulation of specific chromosomal domains in the pluripotent state.

However, in mammals, little or no effect on replication timing regulation has been reported for many chromatin modifier mutants, while these mutations significantly affect gene expression patterns [ 13- 15].

(4) Self-organization and timing regulation module: the ability of the immune system to self-regulation is an important feature of ISR, and failure of such regulation contributes to conditions such as allergy and autoimmune disease [ 5].

Timing regulation of firing, on the other hand, appears to be related to cell type-specific intrinsic chromatin architecture in nuclei.

However, there was a fairly high degree of variation in terms of the timing of regulation amongst transcripts containing this motif, suggesting that other motifs or structural features modulate regulation.

Nothing is known about the function, timing or regulation of the Irga6 GTPase cycle in vivo by heterologous regulators, such as GTPase-activating proteins (GAPs), guanine nucleotide exchange factors or guanine nucleotide dissociation inhibitors (GDIs).

By exploiting both the timing of regulation and spatial variation in children's exposure to highways, I estimate the effect of gasoline content regulation on pollution and child health.

This indicates that the timing of regulation is less important than the 'wiring' of the system in specifying its dynamical behaviour so we were able to use the less computationally expensive synchronous updates of the model for all subsequent runs which is a useful technical aspect but it implies a much more subtle point.

Reporter lines for recombinase activity are necessary to determine the timing, spatial regulation and tissue specificity of recombinase expression [ 14].

We believe that the complex development of the gonad, involving critical timing and regulation of genes, in addition to the pluripotent traits of the PGC, render the developing PGC extremely sensitive to tumor development.

Thus studies in mice and rats are not in agreement, suggesting either species differences and/or differences due to the tools that were used (pharmacological vs. genetic manipulation of the animals) as well as the timing of regulation of PKC (i.e. before and/or during the disease course).