Sentence examples for timing program from inspiring English sources
These equations describe substitution rates corresponding to evolutionary time under the conditions that the replication timing program is stable (genomic sequences are always replicated in the same order) and that the variations of Γ as a function of t rep are conserved so that a given sequence is always replicated in the presence of the same proportion of dCTPs and dGTPs in the pool of dNTPs.
According to this model, local variations of GC3 are linked to temporal variations (averaged over evolutionary time) of, the proportion of dCTPs and dGTPs at time t rep when the sequences are replicated (considering that the replication timing program and the variations of the relative concentrations of dNTPs as functions of t rep have been globally stable).
His firm has worked with each vendor to give them software code that produces a simplified stream that can be more easily interpreted.Predicting when a light will turn green sometimes relies on identifying the particular timing program in place for a signal: some lights run on recurring intervals.
The replication timing program of telomeric regions on human chromosomes might be regulated by specific mechanisms that differ from those for other chromosomal regions.
In this review, we will discuss how the normal replication timing program, as well as how alterations to this program, can contribute to the evolution of the genomic landscape in normal and cancerous cells.
The observation that regenerating axons extend up the antler shaft and branch to form differentiated sensory terminals, while others continue to extend to their targets further up the antler [16], is consistent with an intrinsic timing program for individual neurons.
Our observations suggest that the replication timing programs of the R/G-band boundary and the centromeric region of human chromosome 11q are maintained in CHO h11) cells, whereas that for the telomeric region is altered.
In the present study, we sought to obtain a greater understanding of the relationship between replication timing programs and human chromosomes by analysis of the timing of replication of a single human chromosome 11 that had been transferred into the Chinese hamster ovary (CHO) cell line by chromosome engineering.
This hypothesis would be compatible with a probabilistic model of replication that suggests that predetermined replication timing programs would be artifactually generated by population-based assays (Czajkowsky et al. 2008).
Post-mitotic re-establishment of 3D chromatin architecture occurs at the TDP, and developmental cues that change a replication-timing program are likely to act during this short time window [ 115].
This temporal control of DNA replication is referred to as the replication-timing program.
