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These priorities, however, put minimizing overtime above the patients timing preferences.
This decision was also reinforced from a number of consultations with patients taking sunitinib regarding their randomisation timing preferences.
This is designed to be easily implemented and stays within safety limits of SP in pregnancy; and is not dependent on individual timing preferences for first attendance to antenatal clinic.
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Prepubertal children exhibited a small shift in sleep timing preference between free days and weekdays (Fig. 4).
The difference in sleep timing preference between weekdays and weekends has been aptly described as "social jetlag" [12].
The distance measured in years from the present age to menarche was taken as a biological variable that may affect the change in sleep timing preference.
Thus, it remains unclear whether there is a relation between puberty and this switch in sleep timing preference at the end of adolescence.
One important question about the underlying processes responsible for the switch to advance in sleep timing preference which occurs after 5 years after menarche remains to be examined.
We use stated preference data to compare the valuation of travel time variability under a structural model where trip-timing preferences are defined in terms of time-dependent utility rates, the "slope model", against its reduced-form model.
Sleep duration is associated with single-nucleotide polymorphisms (SNPs) in CLOCK (9), and sleep-timing preference and delayed sleep-phase disorder (DSPD) are associated with polymorphisms within PER2, PER3, and CLOCK, although the results have not always been replicated (2).
The latter is, for example, the case in some interspecific crossing experiments, where the (however weak) pre- and postzygotic barriers (such as differences in germination timing or mating preferences) favor inbreeding (Maclean & Greig, 2008; Morales & Dujon, 2012; Murphy & Zeyl, 2012).
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