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It remains unclear whether these effective neuronal codes are based on spike timing orders and/or amplitudes.
It remains to be examined whether the timing orders of action potentials are solely way for neuronal encoding.
The decoding of brain program that controls cognition and behaviors should be based on spikes' timing orders, such as their sequences, bursts and clusters.
In this regard, the neurons write their codes most likely based on the timing orders of action potentials (i.e., "1-0" digital pattern) similar to "on-off" silicon chips in the computer.
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The timing, order, and appearance of new behavioral elements and causes of behavioral change have been widely investigated.
Therefore, neuronal encoding is likely based on spike timing order, instead of graded analogues.
Genes involved in energy metabolism were also found here with mitochondrial enzymes reaching maximum expression in the first half of G1, while most of the enzymes of the glycolytic pathway had peak timing ordered throughout this cell cycle period (Fig. 3B).
The timing order of the presentation was the same as in Experiment 1.
B) To address the major comment #1, we introduce a phylogenetic tree method to infer timing order of mutations.
In the context of combination ART regimens, confusion can be a major barrier to adherence since these regimens entail following detailed and complex recommendations pertaining to the timing, order and combinations of multiple medications (Ammassari et al., 2001).
A number of algorithms have been developed that allow for solutions that are biologically unfeasible, that is for solutions where some of the switches induce a contradictory timing ordering of the internal vertices of the host tree [ 13, 14, 17, 18].
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