As a learning control, we randomized the relative timing of tone and puff from trial to trial, for a different set of mice.
Two alternative accounts of this striatal activity are possible: "searching" for temporal regularity in early stimulus processing stages or "prediction' of the timing of future tones after the beat is found (relying on continuation of an internally generated beat).
In order to quantify the interval and timing of the tone switches with respect to the syllabic grid, the framework adopts the Fujisaki model for parameterizing F0 contours [1].
When performing simple tone-in-noise detection, thresholds improve when the timing of the potential tone is unambiguous (Watson and Nichols, 1976).
In both cases, successful beat prediction is occurring, but in the latter case, the prediction accuracy is maximal as not only can the beat rate be predicted but also the timing of all other tone onsets in the sequence.
In an e-mail message on Friday morning Ms. Eisenberg offered apologies to "those hurt by this" and wrote that she would be "definitely considering the appropriateness and professionalism of the timing and tone of my communication in the future".
They completed measures of timing perception (comparisons of tempo of tones) and production (rhythmic finger tapping), and general motor skills (Dean–Woodcock Neuropsychological Battery motor tests).
