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The ankle trials were not comparable on intervention, outcomes (injury definition), and timing of outcomes [55,56].
Trade-offs vary with the nature of transportation investment alternatives: timing of outcomes (short run vs. long run), spatial distribution of socio-economic effects (regional vs. national), and who benefits are just some of the trade-offs policymakers face.
The timing of outcomes post hospital discharge are given in Figure 1.
We suggest that future studies should adopt consistent definitions, incorporate baseline and recovery function and consider the timing of outcomes during follow-up.
Although efforts were made to delineate the relationship between timing of outcomes and 5-HT3 RA use, the temporal relationship between these two variables hinged on when providers submitted related claims.
Our model was able to capture the dynamics of Ebola virus disease, including infections resulting from exposure to contaminated syringes and person-to-person transmission, and the timing of outcomes (Fig. 3).
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While studies varied in the timing of outcome assessment (time since the stillbirth), only one study investigated the impact of this timing.
Table 1 summarises timing of outcome measures for the trial and at which time point they will be used.
These studies are heterogeneous (Table 2) in terms of patient selection, time from TBI to MRS, voxel location, method of outcome assessment and timing of outcome assessment.
Two factors potentially associated with treatment effect were examined: study quality and length of follow up (i.e., timing of outcome measurement).
Although our results did not demonstrate a significant effect of structured group reminiscence therapy on overall behavior competency or on physical functioning in elders with dementia, we identified issues related to future implementation of this intervention, such as study power, chosen outcome measures, intervention dose, timing of outcome measures, or cultural applicability issues.
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