This trial is a population-based randomized food and micronutrient intervention where pregnant women were randomly allocated to an early or usual timing of invitation to food supplementation, which included three different micronutrient alternatives.
The main strength of the study is that in a developing country setting where maternal undernutrition, food insecurity, and child mortality are prevalent, MINIMat was a randomised trial with timing of invitation to prenatal food supplementation combined with one of the three types of micronutrients including one already available at the field.
To our knowledge, no other studies have assessed the timing of invitations and the effect on attendance for screening.
The timing of invitations may also be worth considering – although it would require a substantial re-arrangement of current recruitment processes in the bowel screening programmes.
This study, Telemark Polyp Study 1 (TPS-1), achieved an attendance rate of 81%, 4 but it was uncertain if the timing of invitations was important and if this strategy was worth adopting in screening programmes with poor attendance.
Follow-up of invitees until December 2012 allowed for a minimum of 3 months for a response after invitation, any further investigations and minor adjustments made to the timing of screening invitations ('invitation smoothing') for each of the three rounds (BCSP Southern Hub, 2011).
The timing of the invitations lifted eyebrows.
Screening starts at the age of 25 years, based on evidence that harms outweigh benefits in females <25 years. 1 The policy on the timing of the first invitation has been controversial, with many calling for females to be invited at a younger age.
The timing of Washington's invitation to Mr. Kim provides another sign that the countries involved in the talks — which also included China, Russia and Japan — were serious about restarting the negotiations.
"I may agree with some Democrats that the political timing of Netanyahu's invitation may have been unfortunate, and that we must work fervently to keep the US-Israel relationship a strong bipartisan endeavour," Menendez told a conference of the American Israel Public Affairs Committee (Aipac) on Monday.
They recommended that practitioners should consult with someone close to the family, such as the bedside nurse to help establish the appropriate timing of the initial invitation.
