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TMS chronometry did not reveal differences between the timing of functional relevance of PPC and MFG, thus suggesting that they were functionally relevant at the same time.
However, several questions regarding the series and timing of functional and physical gene losses remain unclear, in part because functional data are widely lacking.
TMS chronometry does this by investigating the relative timing of functional relevance for behavior in different brain regions.
However, the timing of functional transfers has been unclear.
3R-derived paralogs could be good examples for evaluating the critical timing of functional differentiation.
Therefore, the timing of functional imaging for therapeutic monitoring must take these factors into account.
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Time-resolved TMS over multiple brain network nodes can elucidate the relative timings of functional relevance for behavior ("TMS chronometry"), while fMRI functional or effective connectivity (fMRI EC) can map task-specific interactions between brain regions based on the interrelation of measured signals.
Again, a simple comparison requires caution because of the different timing of the functional evaluation.
It may also be relevant to the timing of study functional impairment end points in future research.
Consequently, the timing of intensive functional rehabilitation deserves more attention to ensure best possible cumulative gains resulting from spontaneous recovery and therapeutic interventions.
The different timing of neuronal functional maturation observed in the different studies could be explained by high variability in cultures due to the different hPSCs used, different IVND protocols, different seeding density of cells, and other factors related to the IVND protocol used.
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