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We next sought to determine whether the remission (CRM) samples might be distinguishable based on their timing of collection.
Also, timing of collection might play a role in detecting altered peripheral plasma levels of mast cell mediators.
This Montreal-based study used MEMS TrackCap technology to time stamp the collection of samples which may be more reliable than our self-report method of verifying timing of collection: although our cohort was well instructed and reported the actual sampling times.
The timing of collection, transfer on yeasted vials and combination of males and females also mimics the regular maintenance of these populations.
The accuracy of diagnostic tests is known to be affected by the quality of the specimen [10], [11], its handling, the timing of collection after symptom onset, and the age of the patient [14], [15].
Whilst PR can be estimated reasonably quickly, the resulting prevalence is limited by the sensitivity of the assay used and estimates can be profoundly influenced by anti-malarial drug intake and the timing of collection, especially in areas of seasonal transmission; PR also has limited sensitivity to measure changes at the high and low ends of the spectrum of transmission intensities [19].
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The third phase involves both the host (history and mobilization ability) and the performance of the apheresis procedure (apheresis volumes, timing of collections, efficiency, and so on).
Table 2 shows the data to be collected and the timing of data collection.
In addition, collection methods, analytical techniques, analytes measured, and timing of data collection differ.
This lack of sensitivity may be due to the intermittency of virus shedding, the timing of sample collection, and the type of specimens collected.
The timing of plasma collection relative to hemodynamic measurements was not collected in the FACT Trial.
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