Exact(3)
If the timing of aging is to some degree set by developmental processes, then this would help explain the great variability of lifespans observed in nature.
Furthermore, age-associated gene expression changes have been described in homeobox genes (Stelnicki et al., 1998; Wagner et al., 2009) and it is conceivable that they are involved in the timing of aging.
These results provide new pharmacological models for exploring processes that regulate the timing of aging and late-life diseases, and in particular for testing hypotheses about sexual dimorphism in aging and health.
Similar(57)
The timing of age-related somatic degeneration was similar in these groups, suggesting progeny production does not accelerate somatic aging.
In the superior frontal gyrus (SFG), a part of the prefrontal cortex, we observed manifest differences between the two sexes in the timing of age-related changes, that is, sexual heterochrony.
This pushback can and should include the possibility of reforming the way the court does business: Term limits and supermajority requirements, for instance, are both plausible responses to the weirdness of having our great controversies settled by the timing of an aging justice's final illness, or the idiosyncracies of Anthony Kennedy.
Although we attempted to age match animals from different cultivation temperatures based on the well characterized timing of developmental and aging landmarks at various cultivation temperatures (Byerly et al. 1976), slight differences in age could still have occurred.
199 Unfortunately, the exact timing of the age-related decline in BAT is still undetermined as well as the possible impact that age-related leptin resistance could exert on it.
Third, it is possible that individual physical performance levels and/or health status may have changed at different times throughout the 10-year follow-up period, which may have masked the timing of the age-related changes in the different measures.
Initial screening may be based on timing of applications, age, current employment status, etc".
Sensitivity analyses were planned to evaluate the potential effect of timing of TBI, age, drugs and year of publication on efficacy.
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