Exact(40)
Thus management was unblinded, laboratory collection times were not standardised and often incomplete, TPE was variable in timing, dose, repetition frequency and fluid balance, and vasoactive therapy and correction of hypocalcaemia were not standardised.
This system may enable researchers and physicians to remotely regulate the timing, dose, and sequence of drug delivery on-demand, with a wide range of clinical applications ranging from tissue engineering to cancer treatment.
While several studies reveal a significant reduction in AD incidence with prenatal and/or post-natal probiotic supplementation, they differ in the strain(s), timing, dose, treatment duration, and measurement of clinical outcomes.
Because of the retrospective design of the study, precise timing, dose and duration of exposure were not always available, and we could not study the dose-effect relationship.
Studies are required to establish optimal timing, dose and type (natural folate or synthetic folic acid) to prevent birth defects and at the same time minimize adverse effects later in life.
This in vivo response is striking because TGF-β has been shown to inhibit and promote osteoclast differentiation in vitro, depending on the timing, dose and experimental cell population [12].
Similar(20)
Little research has been undertaken with people in the early stages of Parkinson's disease although achieving symptom control depends on regularly timing doses.
If normalization provides the best time during which treatment should be administered, it is important to know when the normalization occurs, and how to optimize timing, dosing and possibly the combinations of drugs administered.
Further research will be necessary regarding whether different timing, dosing, and/or methods of administration may prove more beneficial.
The timing, dosing, and location of thimerosal injections in rodent studies can also have a significant effect on data outcome.
However, the timing, dosing, duration and optimal regimens of chemotherapy drugs to be combined with RT remain controversial.
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